I have always watercooled my PC (AIO's), I see no problems. I used to have a 4790k and got up to 4.6GHz at a 1.23v draw. Was 29c idle and around 65-70 under gaming and rendering load. Obviously can't speak for air cooler or custom water loops. Hope this helped you in any way!
Drama Llama! Thanks for the good time on the way to the rebel outpost yesterday! was good to hear your story and cheers for help to a bunch of noobs :P